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Planta Med 1982; 46(11): 149-152
DOI: 10.1055/s-2007-970040
Research Articles

© Hippokrates Verlag Stuttgart

Medicinal Plants of Surinam

II: Antimicrobial Active Alkaloids from Aspidosperma marcgravianumR. Verpoorte, C. L. M. Ruigrok, A. Baerheim Svendsen
  • Department of Pharmacognosy, State University of Leiden, Gorlaeus Laboratories, Leiden, The Netherlands
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Publication History

1982

Publication Date:
29 March 2007 (online)

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Abstract

From the stem bark of Aspidosperma marcgravianum WOODSON (Apocynaceae) 7 alkaloids were isolated: 4 secamine-type alkaloids - tetrahydrosecamine, decarbomethoxytetrahydrosecamine and two secamine derivatives of unknown structure - and 3 monomeric indole alkaloids - dihydrocorynantheol, 10,11-dimethoxypicraphylline and a hydroxydimethoxypicraphylline derivative. The secamine-type alkaloids and dihydrocorynantheol exhibited antimicrobial activity against grampositive bacteria.

Key Word Index

Aspidosperma marcgravianum - Apocynaceae - Indole alkaloids - Secamine-type alkaloids - Tetrahydrosecamine - Decarbomethoxytetrahydrosecamine - Dihydrocorynantheol - 10,11-dimethoxypicraphylline - Antimicrobial activity