Planta Medica, Inhaltsverzeichnis Planta Med 1982; 46(11): 149-152DOI: 10.1055/s-2007-970040 Research Articles © Hippokrates Verlag Stuttgart Medicinal Plants of Surinam II: Antimicrobial Active Alkaloids from Aspidosperma marcgravianumR. Verpoorte, C. L. M. Ruigrok, A. Baerheim Svendsen Department of Pharmacognosy, State University of Leiden, Gorlaeus Laboratories, Leiden, The Netherlands Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract From the stem bark of Aspidosperma marcgravianum WOODSON (Apocynaceae) 7 alkaloids were isolated: 4 secamine-type alkaloids - tetrahydrosecamine, decarbomethoxytetrahydrosecamine and two secamine derivatives of unknown structure - and 3 monomeric indole alkaloids - dihydrocorynantheol, 10,11-dimethoxypicraphylline and a hydroxydimethoxypicraphylline derivative. The secamine-type alkaloids and dihydrocorynantheol exhibited antimicrobial activity against grampositive bacteria. Key Word Index Aspidosperma marcgravianum - Apocynaceae - Indole alkaloids - Secamine-type alkaloids - Tetrahydrosecamine - Decarbomethoxytetrahydrosecamine - Dihydrocorynantheol - 10,11-dimethoxypicraphylline - Antimicrobial activity PDF (330 kb)
