Synlett 2007(5): 0780-0784  
DOI: 10.1055/s-2007-970771
LETTER
© Georg Thieme Verlag Stuttgart · New York

Stereoselective Access to Functionalized Dihydrophenanthrenes via Reductive Cyclization of Biaryl Ene-Aldehydes

Minoru Tamiya, Corinna Jäger, Ken Ohmori, Keisuke Suzuki*
Department of Chemistry, Tokyo Institute of Technology, SORST-JST, Meguro-ku, Tokyo 152-8551, Japan
Fax: +81(3)57342788; e-Mail: ksuzuki@chem.titech.ac.jp;
Further Information

Publication History

Received 18 December 2006
Publication Date:
08 March 2007 (online)

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Abstract

Stereoselective access to 9-alkyl-10-hydroxy-9,10-dihydrophenanthrenes has been developed via the samarium(II) iodide mediated reductive cyclization of an ene-aldehyde appended to a biphenyl scaffold.