Neue Cardenolide aus Convallaria majalis

Abstract

A detailed study of the cardiac glycosides of Convallaria majalis L. allowed the detection and structure determination of ten new cardenolides. Four glycosides of bipindogenin (bipindogenin-3-0-6′-deoxy-β-D-guloside, bipindogenin-3-0-6′-deoxy-β-D-alloside, bipindogenin-3-0-6′-deoxy-β-D-allosido-α-L-rhamnoside and bipindogenin-3-0-β-D-alloside) were isolated as well as three derivatives of sarmentologenin (sarmentologenin-3-0-α-L-rhamnoside = sarhamnoloside, sarmentologenin-3-0-6′ -deoxy-β-D-guloside and sarmentologenm-3-0-6′-deoxy-β-D-alloside) and three isomeric glycosides of sarmentosigenin A (sarmentosigenin-3-0-α-L-rhamnoside = tholloside, sarmentosigenin-3-0-6′-deoxy-β-D-guloside and sarmentosigenin-3-0-6′-deoxy-β-D-alloside).

The occurrence of allose, and of the disaccharide rhamnosido-6-deoxy-allose, resp. as the sugar moieties of cardiac glycosides, was detected for the first time.

Key Word Index

Convallaria majalis - Liliaceae - Cardenolides - Glycosides of bipindogenin - sarmentologenin - sarmentosigenin