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Planta Med 1982; 45(7): 167-171
DOI: 10.1055/s-2007-971367
Research Articles

© Hippokrates Verlag Stuttgart

Zwei neue Dammaran-Sapogenine aus den Blättern von Panax notoginseng

Two New Dammaran Sapogenins from Leaves of Panax notoginsengWei Junxian1 , Chang Liangyu1 , Wang Jufen1 , Edmund Friedrichs2 , Monika Jores2 , Heinrich Puff2 ,  Chen-Wei-shin3 , Eberhard Breitmaier3
  • 1Yunnan Institute of Materia Medica, Kunming, VR China
  • 2Institut für Anorganische Chemie der Universität Bonn, Bonn, Federal Republic of Germany
  • 3Institut für Organische Chemie und Biochemie der Universität Bonn, Bonn, Federal Republic of Germany
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Publication History

1982

Publication Date:
29 March 2007 (online)

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Abstract

Hydrolysis of the crude saponin extracted from the leaves of Panax notoginseng (BURK.) F. H. CHEN yields five sapogenins which are separated by column chromatography. Two of these are identified to be panaxadiol and panaxatriol whose structures were elucidated earlier. The third sapogenin ist found to be Dammar-20(22)en-3β, 12β,-26-triol by carbon-13 NMR. The structure of the fourth sapogenin is established by X-ray diffractometry and carbon-13 NMR to be 20 (R)-Dammaran-3β, 12β, 20, 25-tetrol.

Key Word Index

Panax notoginseng - Araliaceae - Dammarane sapogenins - Dammar-20(22)en-3β, 12β, 26-triol - 20 (R)-Dammaran-3β, 12β, 20, 25-tetrol - Panaxadiol - Panaxatriol - Triterpenes, tetracyclic