Planta Med 1982; 45(8): 195-202
DOI: 10.1055/s-2007-971372
Research Articles

© Hippokrates Verlag Stuttgart

Neue Cardenolide aus Convallaria majalis

15. Mitteilung über Convallaria-Glykoside1: Strophanthidin-, Cannogenol-, 19-Hydroxy-sarmentogenin- und Sarmentogenin-GlykosideNew Cardenolides from Convallaria majalis B. Kopp, W. Kubelka
  • Institut für Pharmakognosie der Universität Wien
1 14. Mitteilung: Lit. [1] Herrn Prof. T. Reichstein, Basel, zum 85. Geburtstag in herzlicher Verehrung gewidmet.
Further Information

Publication History

1981

Publication Date:
29 March 2007 (online)

Abstract

From the leaves of Convallaria majalis L. eight glycosides of Strophanthidin, cannogenol, sarmentogenin and 19-hydroxysarmentogenin, resp., were isolated and structurally elucidated as strophanthidin-3-O-6′-deoxy-β-D-allosido-α-L-rhamnoside, strophanthidin-3-O-6′-deoxy-β-D-allosido-α-L-arabinoside, strophanthidin-3-O-α-L-rhamnosido-2′-β-D-glucoside, cannogenol-3-O-6′-deoxy-β-D-allosido-β-D-glucoside, cannogenol-3-O-6′-deoxy-β-D-allosido-α-L-rhamnoside, 19-hydroxy-sarmentogenin-3-O-α-L-rhamnoside, sarmentogenin-3-O-6′-deoxy-β-D-allosido-α-L-rhamnoside and sarmentogenin-3-O-6′-deoxy-β-D-guloside, mainly by means of their H-NMR-spectra, by EI-MS and LD-MS.

This is the first report of the occurrence of 19-hydroxy-sarmentogenin in nature. The presence of arabinosido-6-deoxyallose within the sugar chain of a cardiac glycoside was detected for the first time, as well. Including the new glycosides, a total of 38 cardenolides, derived from nine aglycones, have now been found in Convallaria majalis.