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DOI: 10.1055/s-2007-971392
© Hippokrates Verlag Stuttgart
Further Alkaloids from Strychnos dolichothyrsa
Dedicated to Dr. J. L. van Eijk on the occasion of his retirementPublication History
Publication Date:
29 March 2007 (online)
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Abstract
The isolation of one of the major alkaloids and 11 minor alkaloids from the stem bark of Strychnos dolichothyrsa is described. The major alkaloid was identified as bisnor-C-alkaloid H. Two new dimeric alkaloids derived from this alkaloid were found, dolichocurine and dolichothine. For the former alkaloid a structure is proposed. Furthermore, the following minor alkaloids were identified: bisnor-C-alkaloid H N-oxide and di-N-oxide, Wieland Gumlich aldehyde, 18-deoxy Wieland Gumlich aldehyde, 11-methoxy-diaboline, tubotaiwine, Condylocarpine, nor-C-fluorocurarine and nor-macusine B. In the extracts of the stem bark of S. urceolata 11-methoxydiaboline was identified as one of the major alkaloids.
Key Word Index
Strychnos dolichothyrsa - Strychnos urceolata - Loganiaceae - Indole alkaloids - Bisnor-C-alkaloid H - Bisnor-C-alkaloid H N-oxide and di-N-oxide - Dolichocurine - Dolichothine - Wieland Gumlich aldehyde - 18-deoxy Wieland Gumlich aldehyde - 11-Methoxydiaboline - Tubotaiwine - Condylocarpine - Nor-C-fluorocurarine - Normacusine B