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Planta Med 1982; 44(1): 36-40
DOI: 10.1055/s-2007-971397
Research Articles

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Neue herzwirksame Drogen II[*], Nachweis und Isolierung herzwirksamer Amine durch Ionenpaar-HPLC

New Cardioactive Drugs II, Detection and Isolation of Cardiotonic Amines with Ionpair-HPLCH. Wagner, J. Grevel
  • Institut für Pharmazeutische Biologie, Universität München, Bundesrepublik Deutschland
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Publication Date:
29 March 2007 (online)

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Abstract

An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) BRITT et ROSE (Cactus grandiflorus).

Key Word Index

Selenicereus grandiflorus - Cactaceae - Cactus grandiflorus - Ionpair-high-performance-liquid-chromatography - Cardiotonic plant-amines - Tyramine

1 I. Mitteilung: WAGNER, H., M. REITER und W. FERSTL: Planta med. 40, 77 (1980)

1 I. Mitteilung: WAGNER, H., M. REITER und W. FERSTL: Planta med. 40, 77 (1980)