Chemotherapeutic Activity of Polyhalogenated Terpenes from Spanish Algae

A. G. González; V. Darias; E. Estévez

doi:10.1055/s-2007-971399

Planta Medica, Table of Contents

Planta Med 1982; 44(1): 44-46
DOI: 10.1055/s-2007-971399

Research Articles

Chemotherapeutic Activity of Polyhalogenated Terpenes from Spanish Algae[1]

A. G. González, V. Darias, E. Estévez

Instituto de Productos Naturales Orgánicos, CSIC, La Laguna Departamento de Farmacognosia y Farmacodinamia, Universidad de La Laguna, Tenerife, Canary Islands, Spain

Abstract

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Abstract

A study of the cytostatic and antibacterial activity of four halogenated alicyclic monoterpenes obtained from Plocamium cartilagineum L. and of six polyhalogenated sesquiterpenes isolated from two species of Laurencia; L. obtusa HUDS. and L. caespitosa LAMX. is presented. The first monoterpene series was proved to possess higher cytostatic activity. This greater inhibitory activity would seem to be related to a greater presence of halogens in the molecule.

The antibacterial activity of both series may be considered as noticeable although the sesquiterpene compounds isolated from the genus Laurencia proved more active in the tests reported here.

Key Word Index

Algae - Polyhalogenated Terpenes - Cytostatic and Antibacterial Activity

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References

1 A report on this work was presented at the International Research Congress on Natural Products as Medicinal Agents. Strasbourg. July, 1980.