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Planta Med 1982; 44(3): 139-142
DOI: 10.1055/s-2007-971423
Research Articles

© Hippokrates Verlag Stuttgart

Veprisinium Salt, A Novel Antibacterial Quaternary Alkaloid from Vepris louisii

J. Foyere Ayafor, B. Lucas Sondengam, B. Tchaleu Ngadjui
  • Department of Organic Chemistry, University of Yaounde, Yaounde - Cameroon, W. Africa
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Publication History

Publication Date:
29 March 2007 (online)

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Abstract

The water-soluble alkaloid fraction of Vepris louisii G. GILBERT shows significant antibacterial activity. The compound responsible for the activity has been shown to be a novel quaternary dihydrofuroquinoline alkaloid for which the name veprisinium salt is proposed. Its structure has been established primarily by spectral correlation to known alkaloids, chemical conversion to known derivatives and by partial synthesis.

Key Word Index

Vepris louisii - Rutaceae - Veprisinium salt - Quaternary dihydrofuroquinoline alkaloid - Pharmacology - Antimicrobial activity