Studies on Coumarins of a Chinese Drug „Qian-Hu”

Abstract

From the ether-soluble fraction of methanolic extracts of a Chinese Drug “Bai-Hua Quian-Hu”, the root of Peucedanum praeruptorum (Umbelliferae), four coumarin compounds, (±) praeruptorin A, (+) praeruptorin B (= (+) anomalin), Pd-III and Pd-Ib, were isolated. The chemical structures of Pd-III and Pd-Ib have been established to be (+) 3′ (S)-angeroyloxy-4′ (S)-isovaleryloxy-3′, 4′-dihydroseselin and (+) 3′ (R)-angeroyloxy-4′-keto-3′,4′-dihydroseselin, respectively. ¹³C NMR spectra of these compounds are also discussed.

Key Word Index

Peucedanum praeruptorum - Umbelliferae - (+)3′(S)-Angeloyloxy-4′(S)-isovaleryloxy-3′,4′-dihydroseselin - (+)3′(R)-Angeloyloxy-4′-keto-3′,4′-dihydroseselin