Alkaloids from Roots of Aconitum crassicaule

Abstract

From the roots of Aconitum crassicaule, four diterpenoid alkaloids were isolated. Two of these were identified as chasmanine (5) and yunaconitine (4). The other two, Crassicauline A and Crassicauline B, are new alkaloids. The structure of crassicauline A, C₃₅H₄₉O₁₀N, has been elucidated as structure (1) on the basis of chemical and spectral data, while the structure of crassicauline B, C₂₇H₃₁O₄N, is still to be determined.

Key Word Index

Aconitum crassicaule - Ranunculaceae - Diterpenoid alkaloids - Chasmanine - Yunaconitine - Crassicauline A - Crassicauline B