Tranylcypromine Abuse Associated with an Isolated Thrombocytopenia

The authors report a case of a 35-year-old woman with a known history of alcohol abuse, who developed a tranylcypromine abuse with up to 600 mg tranylcypromine daily. She developed a severe thrombocytopenia and secondly a delirious withdrawal syndrome. MAOI causing thrombocytopenia is reviewed and the prescription of tranylcypromine to patients with previous substance abuse is discussed.