Potassium Phosphate Promoted Aza-Markovnikov Addition of N-Heterocycles to Vinyl Esters

Song-wen Lin; Qi Sun; Run-tao Li; Tie-ming Cheng; Ze-mei Ge

doi:10.1055/s-2007-983733

PAPER

Potassium Phosphate Promoted Aza-Markovnikov Addition of N-Heterocycles to Vinyl Esters

Song-wen Lin^a, Qi Sun^a, Run-tao Li*^a,b, Tie-ming Cheng^a, Ze-mei Ge*^a
^a School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. of China
^b State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. of China
Fax: +86(10)82716956; e-Mail: zmge@bjmu.edu.cn;

Abstract

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Abstract

Anhydrous potassium phosphate promoted the aza-Markovnikov addition of a variety of N-heterocycles to vinyl esters in DMF at room temperature in moderate to excellent yields.

Key words

aza-Markovnikov addition - anhydrous K₃PO₄ - N-heterocycles - vinyl esters - 1-[N-(N-heterocycle)]alkyl esters

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Referenzen

References

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