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Synthesis 2007(14): 2175-2185
DOI: 10.1055/s-2007-983761
DOI: 10.1055/s-2007-983761
PAPER
© Georg Thieme Verlag Stuttgart · New York
A Versatile Access to Enantiomerically Pure 5-Substituted 4-Hydroxycyclohex-2-enones: An Advanced Hemisecalonic Acid A Model
Further Information
Received
19 February 2007
Publication Date:
03 July 2007 (online)
Publication History
Publication Date:
03 July 2007 (online)
Abstract
A convenient route for the versatile preparation of 5-substituted 4-hydroxycyclohex-2-enones via the addition of an organocuprate to a cyclohex-2-enone is reported. These compounds are important intermediates in our synthetic studies towards the mycotoxin secalonic acid A.
Keywords
stereoselective synthesis - cyclohexenone - Michael addition - domino reaction - natural products
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References
Characterization details for this compound are available from the authors.