Highly Efficient and Clean Method for Direct α-Iodination of Aromatic Ketones

Guodong Yin; Meng Gao; Nengfang She; Shengli Hu; Anxin Wu; Yuanjiang Pan

doi:10.1055/s-2007-983880

PAPER

Highly Efficient and Clean Method for Direct α-Iodination of Aromatic Ketones

Guodong Yin^a, Meng Gao^a, Nengfang She^a, Shengli Hu^a, Anxin Wu*^a, Yuanjiang Pan*^b
^a Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, Central China Normal University, Wuhan 430079, P. R. of China
e-Mail: chwuax@mail.ccnu.edu.cn;
^b Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China
e-Mail: panyuanjiang@zju.edu.cn;

Abstract

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Abstract

Under neutral reaction conditions, aromatic ketones were transformed into the corresponding α-iodo ketones in high yields by the combination of copper(II) oxide and iodine. The reaction mechanism showed that copper(II) oxide played multiple roles through random self-sorting.

Key words

aromatic ketones - iodine - α-iodo ketones - multifunctional reagent - self-sorting

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Referenzen

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