Interaktion von Depression und körperlichen Erkrankungen

Ulrich Schweiger; Wiebke Greggersen; Eva Fassbinder; Sebastian Rudolf; Susanne Steinlechner; Matthias Nagel; Valerija Sipos

doi:10.1055/s-2007-986201

Psychiatrie und Psychotherapie up2date 2008; 2(1): 21-32
DOI: 10.1055/s-2007-986201

Affektive Störungen

Interaktion von Depression und körperlichen Erkrankungen

Ulrich Schweiger, Wiebke Greggersen, Eva Fassbinder, Sebastian Rudolf, Susanne Steinlechner, Matthias Nagel, Valerija Sipos

Abstract

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Kernaussagen

Depressive Störungen sind ein unabhängiger Risikofaktor für Mortalität.
Die Effektstärke des Risikofaktors Depression ist ähnlich wie die von langjährigem Nikotinmissbrauch.
Depressive Störungen erhöhen spezifisch das Risiko für Diabetes, koronare Herzkrankheit, Herzinfarkt, Herzinsuffizienz und Schlaganfall.
Für eine globale Erhöhung des Risikos für Tumorerkrankungen durch Depression gibt es keine Anhaltspunkte.
Antidepressive Behandlung durch Psychopharmakotherapie und Psychotherapie hat bei Patienten mit Depression und komorbiden körperlichen Erkrankungen eine ähnliche Effektivität wie bei Patienten ohne komorbide Erkrankungen.
Antidepressive Therapie verbessert bei diesen Patienten erheblich die Lebensqualität.
Da Risikofaktoren sich potenzieren (und nicht nur addieren), ist bei Patienten mit Depression und komorbiden körperlichen Erkrankungen ein besonders sorgfältiges Management von weiteren Risikofaktoren empfehlenswert. Ein besonderer Schwerpunkt sollte auf Nikotinabstinenz, Alkoholabstinenz und ausreichende sportliche Betätigung gelegt werden.
Günstige Effekte von antidepressiver Therapie auf den Verlauf körperlicher Erkrankungen konnten bisher nicht mit Sicherheit nachgewiesen werden.

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References

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Prof. Dr. med. Ulrich Schweiger

Klinik für Psychiatrie und Psychotherapie, Universität zu Lübeck

Ratzeburger Allee 160

23538 Lübeck

Phone: 0451/500-2454

Email: ulrich.schweiger@psychiatrie.uk-sh.de