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DOI: 10.1055/s-2007-990263
© Georg Thieme Verlag KG Stuttgart · New York
Structure-Activity Relationship of Triterpenes and Triterpenoid Glycosides against Tobacco Mosaic Virus
Publikationsverlauf
Received: July 24, 2007
Revised: September 27, 2007
Accepted: October 5, 2007
Publikationsdatum:
08. November 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/200714/lookinside/thumbnails/10.1055-s-2007-990263-1.jpg)
Abstract
A new activity of triterpenes and triterpenoid glycosides against phytovirus has been found. Based on the anti-TMV replication activity in vivo, 47 triterpenes and triterpenoid glycosides were screened through the leaf-disk method together with indirect ELISA. Structure-activity relationships were analyzed according to the results of bio-activity screening. Besides, the EC50 values of those compounds having higher activities were measured.
Abbreviations
Cpd(s):compound(s)
DMSO:dimethyl sulfoxide
EC50:median effective concentration
ELISA:enzyme linked immunosorbent assay
SAR:structure-activity relationship
TMV:tobacco mosaic virus
Key words
Structure-activity relationship - triterpenes - triterpenoid glycosides - tobacco mosaic virus (TMV) - EC50
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Prof. Ming-An Ouyang
Institute of Plant Virology
Fujian Agriculture and Forestry University
Fuzhou
Fujian 350002
People’s Republic of China
Telefon: +86-591-8379-3817
eMail: maouyang@yahoo.com