Simple and Efficient Synthesis of N-Quaternary Salts of Quinuclidinium Derivatives

Jean-Yves Kazock; Mohamed Taggougui; Bernard Carré; Patrick Willmann; Daniel Lemordant

doi:10.1055/s-2007-990908

SHORTPAPER

Simple and Efficient Synthesis of N-Quaternary Salts of Quinuclidinium Derivatives

Jean-Yves Kazock*^a, Mohamed Taggougui^a, Bernard Carré^a, Patrick Willmann^b, Daniel Lemordant^a
^a Laboratoire Chimie Physique des Interfaces et des Milieux Electrolytiques, Faculté des Sciences, Université de Tours, Parc de Grandmont, Bat. J, 37200 Tours, France
Fax: +33(2)47367073; e-Mail: jykazock@yahoo.fr;
^b CNES, 18 Avenue E. Belin, 31055 Toulouse cedex, France

Abstract

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Abstract

The rapid and efficient synthesis of 1-alkylquinuclidinium (1-alkyl-1-azabicyclo[2.2.2]octane) and 1-alkyl-4-aza-1-azoniabicyclo[2.2.2]octane iodides are described. The products were characterized by ¹H NMR spectra and elemental analysis.

Key words

amines - alkyl halides - alkylation - ammonium - ionic liquids

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