Preparation of 1,2-Dihydroisoquinolines by a Three-Component Reaction under Catalyst-Free Conditions

Abstract

A variety of 1,2-dihydroisoquinoline derivatives have been efficiently prepared by a three-component reaction using ortho-alkynylbenzaldehydes, primary amines, and pronucleophiles under mild catalyst-free conditions.

Key words

catalyst-free conditions - 1,2-dihydroisoquinoline - direct addition - multicomponent reaction - pronucleophile

References

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