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Am J Perinatol 1996; 13(5): 301-303
DOI: 10.1055/s-2007-994346
ORIGINAL ARTICLE

© 1996 by Thieme Medical Publishers, Inc.

Hypoxemia Associated with Cimetidine Therapy in a Newborn Infant

Jacob Kuint, Nehama Linder, Brian Reichman
  • Department of Neonatology, The Chaim Sheba Medical Center, Tel-Hashomer and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
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Publication Date:
04 March 2008 (online)

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ABSTRACT

Cimetidine therapy used for the treatment of gastric bleeding due to tolazoline therapy in a newborn infant was temporally associated with episodes of severe hypoxemia. It appears likely that the histamine H2 receptor blocked by cimetidine obviated the pulmonary vasodilator effect of tolazoline therapy.

Keywords

Cimetidine therapy - hypoxemia - histamine