Am J Perinatol 1996; 13(6): 355-361
DOI: 10.1055/s-2007-994356
ORIGINAL ARTICLE

© 1996 by Thieme Medical Publishers, Inc.

Prenatal Diagnosis and Perinatal Aspects of Abdominal Wall Defects

Chih-Ping Chen, Fen-Fen Liu, Sheau-Wen Jan, Jin-Cherng Sheu, Shih-Hung Huang, Chung-Chi Lan
  • Departments of Obstetrics and Gynecology, Medical Research, Pediatric Surgery, and Pathology, Mackay Memorial Hospital, Taipei, Taiwan, Republic of China
Further Information

Publication History

Publication Date:
04 March 2008 (online)

ABSTRACT

We retrospectively reviewed 27 cases of omphalocele and 15 cases of gastroschisis occurring among 62,572 deliveries between 1987 and 1994. All cases had undergone prenatal sonographic examinations at a mean gestational age of 28 weeks. In cases of omphalocele, 59.3% (16/27) of fetuses were associated with multiple malformations and 16% (4/25) had chromosomal abnormalities. Among the 4 cases with an abnormal karyotype, three cases were associated with extracorporeal livers and two cases were associated with umbilical cord cysts. Prenatal ultrasound examinations during the second and third trimesters were able to detect 66.7% (18/27) of the cases of omphalocele and 66.7% (10/15) of the cases of gastroschisis. Failure in correctly diagnosing abdominal wall defects by prenatal ultrasound occurred mostly in cases associated with small defects, ruptured omphalocele, multiple fetal anomalies, intrauterine fetal death, twin pregnancies, or cases referred in late gestation. A comparison of perinatal data between omphalocele and gastroschisis reveals fetuses with omphalocele carry higher risks of associated malformations, chromosomal abnormalities, prematurity, and neonatal death. Although fetuses with gastroschisis have higher incidences of oligohydramnios and small for gestational age, the fetal prognosis after pediatric surgery is good.