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DOI: 10.1055/s-2007-995502
© Georg Thieme Verlag KG Stuttgart · New York
Fetale Magnetresonanztomographie des Gehirns
Fetal magnetic resonance imaging of the brainPublikationsverlauf
Publikationsdatum:
07. März 2008 (online)
Zusammenfassung
Die fetale Magnetresonanztomographie (MRT) ist eine wertvolle Ergänzung der Ultrasonographie (US) in der pränatalen Diagnostik. Insbesondere in der Diagnostik komplexer Pathologien des Zentralnervensystems sind die hohe räumliche Auflösung, das große Blickfeld, die verschiedenen Kontraste, welche in der MRT erzeugt werden können, und der Einsatz funktioneller MR-Sequenzen von großem Vorteil. Zudem wird die fetale MRT nicht gestört von überlagernden ossären maternalen oder fetalen Strukturen, intestinalem Meteorismus oder maternaler Obesitas. Die Entwicklung ultraschneller Bildsequenzen erübrigt eine fetale Sedierung. Heute wird die fetale MRT eingesetzt, um schwerwiegende US-Diagnosen zu bestätigen, zu ergänzen oder zu korrigieren, damit der Fetus sowohl pränatal als auch postnatal optimal betreut wird.
Abstract
Fetal magnetic Resonance Imaging (MRI) is a valuable adjunct to ultrasonography (US) in prenatal diagnosis. The high spatial resolution, the large field-of-view, the different contrasts that can be generated and the development of functional MRI-sequences are especially valuable in the diagnosis of complex pathologies of the central nervous system. In addition, fetal MRI does not suffer from obscuring maternal or fetal osseous structures, intestinal gas or maternal obesitas. The ultrafast MRI sequences allow imaging without fetal sedation. Nowadays, fetal MRI is used to confirm, complete or correct US-findings in order to offer the best possible fetal treatment pre- and postnatally.
Key words
Fetal magnetic resonance imaging · MR-Sequences · brain development · central nervous system · fetal pathology · pitfalls
Literatur
- 1 Huisman T A, Martin E, Kubik . Huch R, Marincek B. Fetal magnetic resonance imaging of the brain: technical considerations and normal brain development. Eur Radiol. 2002; 12 1941-1951
- 2 Huisman T A, Wisser J, Martin E, Kubik-Huch R, Marincek B. Fetal magnetic resonance imaging of the central nervous system: a pictorial essay. Eur Radiol. 2002; 12 1952-1961
-
3 Girard N, Huisman T A.
Fetal magnetic resonance imaging of the central nervous system. In: Tortori-Donati P (ed) Pediatric neuroradiology. Berlin; Springer 2005: 1219-1253 - 4 Glenn O A, Barkovich A J. Magnetic resonance imaging of the fetal brain and spine: An increasingly important tool in prenatal diagnosis, Part 1. AJNR Am J Neuroradiol. 2006; 27 1604-1611
- 5 Glenn O A, Barkovich J. Magnetic resonance imaging of the fetal brain and spine: An increasingly important tool in prenatal diagnosis, Part 2. AJNR Am J Neuroradiol. 2006; 27 1807-1814
- 6 Garel C. New advances in fetal neuroimaging. Pediatr Radiol. 2006; 36 621-625
- 7 Girard N, Chaumoitre K, Confort-Gouny S, Viola A, Levrier O. Magnetic resonance imaging and the detection of fetal brain anomalies, injury, and physiologic adaptations. Curr Opin Obstet Gynecol. 2006; 18 164-176
- 8 Blondin D, Turowski B, Schaper J. Fetal MRI. Fortschr Röntgenstr. 2007; 179 111-118
- 9 Schneider J F, Confort-Gouny S, Le Fur Y. et al . Diffusion-weighted imaging in normal fetal brain maturation. Eur Radiol. 2007; [Epub ahead of print]
- 10 Girard N, Fogliarini C, Viola A. et al . MRS of normal and impaired fetal brain development. Eur J Radiol. 2006; 57 217-225
- 11 Fogliarini C, Chaumoitre K, Chapon F, Fernandez C, Levrier O, Figarella-Branger D, Girard N. Assessment of cortical maturation with prenatal MRI. Part I: Normal cortical maturation. Eur Radiol. 2005; 15 1671-1685
- 12 Fogliarini C, Chaumoitre K, Chapon F, Fernandez C, Levrier O, Figarella-Branger D, Girard N. Assessment of cortical maturation with prenatal MRI. Part II: abnormalities of cortical maturation. Eur Radiol. 2005; 15 1781-1789
- 13 Prayer D, Kasprian G, Krampl E, Ulm B, Witzani L, Prayer L, Brugger P C. MRI of normal fetal brain development. Eur J Radiol. 2006; 57 199-216
- 14 Prayer D, Brugger P C, Kasprian G, Witzani L, Helmer H, Dietrich W, Eppel W, Langer M. MRI of fetal acquired brain lesions. Eur J Radiol. 2006; 57 233-249
- 15 Kanal E, Borgstede J P. et al . American College of Radiology white paper on MR safety. AJR Am J Roentgenol. 2002; 178 1335-1347
- 16 Mehta T S, Levine D. Imaging of fetal cerebral ventriculomegaly: A guide to management and outcome. Semin Fetal Neonatal Med. 2005; 10 421-428
- 17 Garel C, Chantrel E, Elmaleh M, Sebag G. Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination. Child’s Nerv Syst. 2003; 19 422-425
- 18 Garel C, Chantrel E, Brisse H, Elmaleh H, Luton D, Oury J F, Sebag G, Hassan M. Fetal cerebral cortex: Normal gestational landmarks identified using prenatal MR imaging. AJNR Am J Neuroradiol. 2001; 22 184-189
- 19 Garel C. The role of MRI in the evaluation of the fetal brain with an emphasis on biometry, gyration and parenchyma. Pediatr Radiol. 2004; 34 694-699
-
20 Garel C.
Methodology and results. In: Garel C (ed) MRI of the fetal brain. Normal development and cerebral pathologies. Berlin; Springer 2004: 13-114 - 21 Gupta J K, Bryce F C, Lilford R J. Management of apparently isolated fetal ventriculomegaly. Obstet Gynecol Surv. 1994; 49 716-721
- 22 Levine D, Barnes P D, Madsen J R, Abbott J, Mehta T, Edelmann R R. Central nervous system abnormalities assessed with prenatal magnetic resonance imaging. Obstet Gynecol. 1999; 94 1011-1019
- 23 Wagenvoort A M, Bekker M N, Go A T, Vandenbussche F P, van Buchem M A, Valk J, van Vugt J M. Ultrafast scan magnetic resonance in prenatal diagnosis. Fetal Diagn Ther. 2000; 15 364-372
- 24 Sonigo P C, Rypens F F, Carteret M, Delezoide A l, Brunelle F O. MR imaging of fetal cerebral anomalies. Pediatr Radiol. 1998; 28 212-222
Thierry A. G. M. Huisman
Division Pediatric
Johns Hopkins Hospital
600 North Wolfe Str.
Nelson, B-173
Baltimore, MD 21287-0842
USA
Telefon: ++1/410/9556140
Fax: ++1/410/5023633
eMail: thuisma1@jhmi.edu