Summary
Healthy male volunteers injected subcutaneously with 200 mg L-GABOB showed no significant
changes in plasma GH, prolactin and cortisol levels. On the other hand, an intrathecal
injection of 300 mg D, L-GABOB to cerebrovascular patients caused significant increases
in plasma GH, prolactin and cortisol levels at 60 min after injection. These results
indicate that GABOB may elicit the secretion of GH, prolactin and ACTH via the central
nervous system.
Key-Words
GABOB - GH - Prolactin - Cortisol - Human Subjects
