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Horm Metab Res 1980; 12(10): 537-540
DOI: 10.1055/s-2007-999193
© Georg Thieme Verlag, Stuttgart · New York

Serum Coenzyme Q10 Levels in Thyroid Disorders

F. Ogura, H. Morii, M. Ohno, T. Ueno, S. Kitabatake1 , N. Hamada2 , K. Ito2
  • Second Department of Internal Medicine, Osaka City University, Abeno, Osaka, Japan
  • 1Statistical Laboratory, Osaka City University, Abeno, Osaka, Japan
  • 2Ito Hospital, Shibuya, Tokyo, Japan
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Publication History

1979

1980

Publication Date:
14 March 2008 (online)

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Summary

The correlation between serum CoQ10 levels and serum thyroid hormones in thyroid disorders was investigated in the present studies. Serum CoQ10 was measured by high speed liquid chromatography utilizing ultraviolet detector. In normal controls, serum CoQ10 level of the male was higher than that of the female. Serum CoQ10 level in hyperthyroidism was significantly lower than that of euthyroid subjects. But in hypothyroidism, serum CoQ10 level did not show any significant difference from that of euthyroid subjects. Significant inverse correlations were demonstrated between log CoQ10 and log T3, log T4, log free T4, or log rT3. These data suggested abnormalities in the mitochondrial electron transport system in thyroid disorders.

Key-Words

Serum Coenzyme Q10 - Thyroid Disorders