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Am J Perinatol 1992; 9(5/06): 326-328
DOI: 10.1055/s-2007-999256
ORIGINAL ARTICLE

© 1992 by Thieme Medical Publishers, Inc.

Comparison of Fetal Lung Maturation in Preterm Singleton and Twin Pregnancies

Hung N. Winn, Roberto Romero, Andreas Roberts, Haitang Liu, John C. Hobbins
  • Divisions of Maternal-Fetal Medicine, Departments of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut and Washington University School of Medicine, St. Louis, Missouri
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Publication Date:
04 March 2008 (online)

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ABSTRACT

Preterm labor or premature rupture of membranes is one of the major complications of twin pregnancies and contributes to the increased maternal and perinatal morbidity and mortality. Forty-seven twin pregnancies and a comparable group of singleton pregnancies constitute the study population. These patients' pregnancies were complicated only by preterm labor. The lecithin to sphingomyelin ratio is used as an index of fetal lung maturation. Analysis of the data reveals that fetal lung maturation is biochemically comparable between twin and singleton pregnancies and among twins for a given gestational age in this clinical setting.