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Am J Perinatol 1991; 8(1): 37-38
DOI: 10.1055/s-2007-999336
ORIGINAL ARTICLE

© 1991 by Thieme Medical Publishers, Inc.

Outcome of Pregnancy after First Trimester Exposure to H2 Receptor Antagonists

Gideon Koren, Donna M. Zemlickis
  • The Motherisk Clinic, Division of Clinical Pharmacology, Department of Pediatrics, and The Research Institute, The Hospital for Sick Children, Toronto, Ontario
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Publication Date:
04 March 2008 (online)

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ABSTRACT

H2 antagonists are widely prescribed medications and are often consumed by women who are unaware of being pregnant. In 23 cases reported to the Motherisk program there were two spontaneous abortions, two therapeutic abortions, 18 normal births, and one infant with a large hemangioma of the upper right eyelid. The hemangioma was removed without incident. Our data suggest that cimetidine and ranitidine may not be teratogenic risk in humans.