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Am J Perinatol 1989; 6(1): 69-71
DOI: 10.1055/s-2007-999548
ORIGINAL ARTICLE

© 1989 by Thieme Medical Publishers, Inc.

Micropenis and Congenital Adrenal Hypoplasia

Michael J. Bourgeois, Brinders Jones, David C. Waagner, Dale Dunn
  • Departments of Pediatrics and Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas
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Publication Date:
04 March 2008 (online)

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ABSTRACT

Micropenis is often an early sign of congenital hypopituitarism. It has also been associated with congenital adrenal hypoplasia in infants with anencephaly and pituitary agenesis. This report is on two infants with micropenis and congenital adrenal hypoplasia. One presented with a similar clinical course and postmortem findings to previously reported cases of adrenal hypoplasia and pituitary agenesis. The other patient represents the first reported case of an infant with micropenis and congenital adrenal hypoplasia in the absence of pituitary agenesis. The histologic patterns of adrenal hypoplasia, as well as the etiologic and clinical implications of its association with micropenis, are discussed.