RSS-Feed abonnieren
DOI: 10.1055/s-2008-1027287
© Georg Thieme Verlag KG Stuttgart · New York
Akute Calciumpyrophosphatdihydrat-Arthritis bei Kniearthroplastik
Acute Calcium Pyrophosphate Dihydrate Arthritis in Total Knee ArthroplastyPublikationsverlauf
Publikationsdatum:
27. August 2008 (online)
Zusammenfassung
Bisher sind erst einzelne Fälle einer Calciumpyrophosphat-Arthritis in einem Kunstgelenk publiziert worden. Wir berichten über eine 63-jährige Patientin mit einer akuten Arthritis in einer sechs Jahre zuvor implantierten Kniearthroplastik. Der negative Nachweis von Mikroorganismen sowie das Vorhandensein von Calciumpyrophosphatdihydrat-Kristallen in der Gelenksflüssigkeit und im Synovialgewebe führten zur Diagnose einer Calciumpyrophosphatdihydrat-Arthritis. Die Symptomatik und die Entzündungszeichen waren unter konservativer Therapie regredient. Eine Antibiotikagabe oder ein Prothesenausbau waren nicht notwendig. Es werden differenzialdiagnostische Überlegungen insbesondere zur Abgrenzung von einer Protheseninfektion angestellt.
Abstract
Only few cases of acute calcium pyrophosphate dihydrate arthritis in total knee arthroplasty have been published. We report about a 63-year-old woman with an acute arthritis occurring six years after implantation of a total knee arthroplasty. The negative culture results and the identification of calcium pyrophosphate dihydrate crystals in synovial fluid and synovial tissue provided the diagnosis of pseudogout arthritis. The patient recovered under conservative treatment. Antibiotics or retrieval of the implant were unnecessary. Exclusion of an implant infection is of the utmost importance.
Schlüsselwörter
Calciumpyrophosphatdihydrat-Arthritis - Kniearthroplastik - Protheseninfektion
Key words
calcium pyrophosphate dihydrate arthritis - knee arthroplasty - prosthesis infection
Literatur
- 1 Atkins B L, Athanasou N, Deeks J J. et al . Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty. J Clin Microbiol. 1998; 36 2932
- 2 Berbari E F, Hanssen A D, Duffy M C. et al . Risk factors for prosthetic joint infection: Case control study. Clin Infect Dis. 1998; 27 1247
- 3 Costerton J W, Stewart P S, Greenberg E P. Bacterial biofilms: a common cause of persistent infections. Science. 1999; 284 1318
- 4 Crawford R, Puddle B, Hunt N. et al . Deposition of calcium pyrophosphate in tissue after revision arthroplasty of the hip. J Bone Joint Surg. 1999; 81 (B) 552-554
- 5 Doll N J, Jackson F. Acute pseudogout simulatin septic arthritis. JAMA. 1979; 242 1768
- 6 Donlan R M. Biofilm formation: a clinically relevant microbiological process. Clin Infect Dis. 2001; 33 1387
- 7 Ellman M H, Levin B. Chondrocalcinosis in elderly persons. Arthritis Rheum. 1975; 18 43
- 8 Fam A G, Topp J R, Stein H. et al . Clinical and roentgenographic aspects of pseudogout: a study of 50 cases and a review. CMA Journal. 1981; 124 545-549
- 9 Hirose B C, Wright R W. Calcium pyrophosphate dihydrate deposition disease (pseudogout) after total knee arthroplasty. J Arthroplasty. 2007; 22 273-276
- 10 Holt G, Vass C, Kumar D S. Acute crystal arthritis mimicking infection after total knee arthroplasty. MJ. 2005; 331 1322-1323
- 11 Lohmann C H, Fürst M, Niggemeyer O. et al . Die Behandlung von periprothetischen Infektionen. Z Rheumatol. 2007; 66 28-33
- 12 Radcliffe K, Pattrick M, Doherty M. Complications resulting from misdiagnosing pseudogout as sepsis. British Medical Journal. 1986; 293 440-441
- 13 Rosenthal A K, Ryan L M, McCarty D J. Calcium pyrophosphate crystal deposition disease, pseudogout, and articular chondrocalcinosis. Koopman WJ ( Arthritis and Allied Conditions Philadelphia; Lippincott Williams&Wilkins 2001 14th ed: 2348
- 14 Rosenthal A K, Ryan L M. Calcium pyrophosphate crystal deposition disease, pseudogout and articular chondrocalcinosis. Koopnan WJ, Moreland LW Arthritis and Allied Conditions Philadelphia; Lippincott, Williams and Wilkins 2005 15th ed: 2373
- 15 Shah K, Spear J, Nathanson L A. et al . Does the presence of crystal arthritis rule out septic arthritis?. J Emerg Med. 2007; 32 23-26
- 16 Smith S L, Wastie M L, Forster I. Radionuclide bone scintigraphy in the detection of significant complications after total joint replacement. Clin Radiol. 2001; 56 221
- 17 Sonsale P D, Philipson M R. Pseudogout after total knee arthroplasty. J Arthroplasty. 2007; 22 271-272
- 18 Trampuz A, Piper K E, Jacobson M J. et al . Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med. 2007; 357 654
- 19 Trampuz A. et al . Synovial fluid leucocyte count and differential for diagnosis of prosthetic knee infection. Am J Med. 2004; 117 556-562
- 20 Widmer A F. New developments in diagnosis and treatment of infection in orthopedic implants. Clin Infect Dis. 2001; 33 (Suppl 2) S94
- 21 Zimmerli W, Trampuz A Ochsner PE. Prosthetic-joint infections. N Engl J Med. 2004; 351 1645
Dr. Anna Thoma
Rheumatologie, Schulthess Klinik
Lengghalde 2
8008 Zürich, Schweiz
Telefon: ++ 41/44/3 85 74 76
Fax: ++ 41/44/3 85 75 38
eMail: anna.thoma@gmx.ch