Synlett 2008(3): 301-312  
DOI: 10.1055/s-2008-1032058
ACCOUNT
© Georg Thieme Verlag Stuttgart · New York

[8+2] Cycloaddition Reactions in Organic Synthesis

Vijay Nair*a,b, K. Gopalakrishnan Abhilasha
a Organic Chemistry Section, Regional Research Laboratory (CSIR), Trivandrum 695 019, India
b Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India
Fax: +91(471)2491712; e-Mail: vijaynair_2001@yahoo.com;
Further Information

Publication History

Received 4 May 2007
Publication Date:
16 January 2008 (online)

Abstract

Higher-order cycloaddition reactions offer great promise as a facile method for the synthesis of medium-sized ring systems. [8+2] Cycloaddition reactions are especially attractive in this regard. The present account summarizes the important applications of [8+2] cycloaddition reactions in organic synthesis.

1 Introduction

2 Heptafulvenes

3 Tropone

4 Tropothione

5 Azaheptafulvenes

6 Other Systems

7 Conclusion