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Int J Sports Med 1981; 02(2): 101-105
DOI: 10.1055/s-2008-1034591
© Georg Thieme Verlag Stuttgart · New York

Structural Alterations of Liver Parenchyma Induced by Anabolic Steroids*

C. Stang-Voss, H.-J.  Appell
  • Institut für Experimentelle Morphologie der Deutschen Sporthochschule Köln
* This article is cordially dedicated to Professor Dr. Jochen Staubesand on the occasion of his 60th birthday.
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Publikationsdatum:
14. März 2008 (online)

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Abstract

The long-term effects of an anabolic steroid (Dianabol) on the liver of motor-active mice was investigated. The pathologic changes occurring are due to cholestasis, peliosis hepatis, and diffuse hepatitis. It was assumed that a pathogenic relationship between cholestasis, peliosis, and cirrhosis exists. Neoplasms seldom occurred, but it was suggested that anabolic steroids do not primarily induce the formation of liver tumors.

Key words

anabolic steroids - liver - ultrastructure - mouse