RSS-Feed abonnieren
DOI: 10.1055/s-2008-1038783
© Georg Thieme Verlag KG Stuttgart · New York
Early and Late Results of Permanent Atrial Fibrillation Ablation Surgery in Aortic Valve and CABG Patients
Publikationsverlauf
received Dec. 20, 2007
Publikationsdatum:
22. September 2008 (online)
Abstract
Objective: The study investigates the early and late results of permanent atrial fibrillation (AF) ablation surgery concomitant to coronary artery bypass grafting (CABG) and/or aortic valve (AV) surgery. Methods: Between February 2001 and April 2006, a selective group of 80 patients with permanent AF (median: 48 months [Perc25/75 24/110; range: 6 – 360 months]) underwent either bipolar (n = 60) or monopolar (n = 20) radiofrequency (RF) ablation procedures concomitant to CABG and/or AV surgery (CABG: n = 39; AV: n = 30; AV + CABG: n = 11). All patients were restudied to assess survival, conversion rate to stable sinus rhythm (SR) and New York Heart Association (NYHA) class early (3 ± 1 months) and late after surgery (30 ± 15 months). Data were analyzed exploratively. Results: Survival at 3 and 30 months was 98 % and 96 %, respectively. Stable SR could be documented in 73 % and 77 % of patients. Long-term AF before surgery and larger LA size were predictive for AF return after surgery (p = 0.004 and p = 0.032, respectively). Neither age, gender, the application modus of the RF energy nor the underlying cardiac disease influenced the postoperative cardiac rhythm significantly. NYHA class improved significantly after surgery (p < 0.0005), particularly when stable SR was achieved (p = 0.049). Conclusion: Preoperative permanent AF duration time and larger LA size are useful variables to predict the success rate of concomitant ablation surgery in CABG and/or AV patients. Further it could be demonstrated that established SR remained stable over time.
Key words
aortic valve surgery - arrhythmia surgery - atrial fibrillation - coronary artery bypass grafting - radiofrequency ablation
References
- 1 Moe G K. On the multiple wavelet hypothesis of atrial fibrillation. Arch Int Pharmacodyn Ther. 1962; 140 183-188
-
2 Allessie M, Lammers W JEP, Bunke F I, Hollen J.
Experimental evaluation of Moe's multiple wavelet hypothesis of atrial fibrillation. Zipes D, Jalife J, eds. Cardiac electrophysiology and arrhythmias. New York; Cruno and Straiton 1985: 265-275 - 3 Wijffels M CEF, Kirchhof C JHJ, Doland R. et al . Atrial fibrillation begets atrial fibrillation. Circulation. 1995; 92 1954-1968
- 4 Haissaguerre M, Jais P, Shah D C, Takahashi A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Metayer P, Clementy J. Spontaneous initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins. N Engl J Med. 1998; 339 659-666
- 5 Cox J L, Schuessler R B, Lappas D G, Boineau J P. An 8 œ years clinical experience with surgery for atrial fibrillation. Ann Thorac Surg. 1996; 224 267-275
- 6 Melo J, Andragao P, Neves J, Ferreira M, Timoteo A, Santiago T, Ribeiras R, Canada M. Endocardial and epicardial radiofrequency ablation in the treatment of atrial fibrillation with a new intraoperative device. Eur J Cardiothorac Surg. 2000; 18 182-186
- 7 Benussi S, Pappone C, Nascimbene S, Oreto G, Caldarola A, Stefano P L, Casati V, Alfieri O. A simple way to treat chronic atrial fibrillation during mitral valve surgery: the epicardial radiofrequency approach. Eur J Cardiothorac Surg. 2000; 17 524-529
- 8 Li D, Fareh S, Leung T K, Nattel S. Promotion of atrial fibrillation by heart failure in dogs. Atrial remodeling of a different sort. Circulation. 1999; 100 87-95
- 9 Goette A, Staack T, Röcken C, Arndt M, Geller J C, Huth C, Ansorge S, Klein H U, Lendeckel U. Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation. J Am Coll Cardiol. 2000; 35 1669-1677
- 10 Kawara T, Derksen R, de Groot J R, Coronel R, Tasseron S, Linnenbank A C, Hauer R NW, Kirkels H, Janse M J, de Bakker J MT. Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis. Circulation. 2001; 104 3069-3075
- 11 Jahangiri M, Weir G, Mandal K, Savelieva I, Camm J. Current strategies in the management of atrial fibrillation. Ann Thorac Surg. 2006; 82 357-364
- 12 Bakir I, Casselmann F P, Brugada P, Geelen P, Wellens F, Degrieck I, Van Praet F, Vermeulen Y, De Geest R, Vanermen H. Current strategies in the surgical treatment of atrial fibrillation: review of the literature and Onze Lieve Vrouw Clinic's strategy. Ann Thorac Surg. 2007; 83 331-340
- 13 Roy D, Talajic M, Dorian P, Connolly S, Eisenberg M J, Green M, Kus T, Lambert J, Dubuc M, Gagne P, Nattel S, Thibault B. Amiodarone to prevent recurrence of atrial fibrillation. N Engl J Med. 2000; 342 913-920
- 14 Khargi K, Laczkovics A, Haardt H. et al .Concomitant anti-arrhythmic procedures to treat permanent atrial fibrillation in CABG and AVR patients are as effective as in mitral valve patients. Read at the 3rd EACTS/ESTS Joint Meeting, Leipzig, Germany, 15th September 2004 2004
- 15 Geidel S, Ostermeyer J, Laß M, Geisler M, Kotetishvili N, Aslan H, Boczor S, Kuck K H. Permanent atrial fibrillation ablation surgery in CABG and aortic valve patients is at least as effective as in mitral valve disease. Thorac Cardiovasc Surg. 2006; 54 91-95
- 16 Gillinov A M, Pettersson G, Rice T W. Esophageal injury during radiofrequency ablation for atrial fibrillation. J Thorac Cardiovasc Surg. 2001; 122 1239-1240
-
17 Melo J, Berglin E, Sie H, Benussi S, Knaut M, Williams M, Hornero F, Marinelli G, Fulquet-Carreras E, Ridley P. Surgery for atrial fibrillation in mitral patients with and without additional procedures. Results at 5 years from an international registry. [Presented at the 86th AATS Annual Meeting, Philadelphia, PA, USA, 29.04. – 03. 05. 2006]
Dr. Stephan Geidel
Asklepios Klinik St. Georg
Abteilung für Herzchirurgie
Lohmuehlenstraße 5
20099 Hamburg
Germany
eMail: s.geidel@asklepios.com
eMail: Stgeidel@aol.com