Exp Clin Endocrinol Diabetes 2008; 116(6): 352-356
DOI: 10.1055/s-2008-1042403
Article

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Vitamin D Deficiency among Pregnant Women and Their Newborns in Isfahan, Iran

M. Salek 1 , M. Hashemipour 1 , A. Aminorroaya 2 , A. Gheiratmand 1 , R. Kelishadi 3 , P. M. Ardestani 4 , H. Nejadnik 4 , M. Amini 2 , B. Zolfaghari 5
  • 1Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran
  • 2Isfahan Endocrine & Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • 3Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • 4Medical School, Isfahan University of Medical Sciences, Isfahan, Iran
  • 5Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
Weitere Informationen

Publikationsverlauf

received 29.08.2007 first decision 25.10.2007

accepted 20.12.2007

Publikationsdatum:
25. März 2008 (online)

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Abstract

Background and aims: Vitamin D deficiency is one of the major health problems and unexpectedly has a high prevalence in sunny countries (e.g. Middle East). In this study we determined the prevalence of vitamin D deficiency in pregnant women and their newborns in Isfahan, a sunny city in Iran.

Methods: In a cross-sectional study, 88 newborns born in Beheshty hospital, affiliated to Isfahan University of Medical Sciences (August-September, 2005) and their mothers were studied. Their data were collected by questionnaires and blood sampling was done to measure serum alkaline phosphatase (ALP), calcium, phosphorus, 25(OH) vitamin D and parathormone (PTH). Vitamin D deficiency defined as levels of 25(OH) D<20 and <12.5 ng/ml for mothers and newborns, respectively and local cut-offs defined as levels in which mean serum PTH started to increase.

Results: The prevalence of vitamin D deficiency according to 25(OH) D<20ng/ml in mothers and <12.5 ng/ml in newborns was 5.7% and 4.5%, respectively. According to local cut-offs (35 ng/ml for mothers and 26 ng/ml for newborns) 26.1% of mothers and 53.4% of newborns were vitamin D deficient.

Conclusion: According to local definition, vitamin D deficiency is a health problem in pregnant women and their newborns in this sunny city.

References

Correspondence

P.M. ArdestaniMD 

No 66, 10th street

Mollasadra street

Darvazeh Shiraz

Isfahan

Iran

Telefon: +98/91/3310 38 41

Fax: +98/311/668 50 97

eMail: pooneh_ardestani@yahoo.com