Zur Mononatriumuratkristallablagerung im Femurkopf bei Osteonekrose*

Abstract

38 patients with osteonecrosis of the hip were examined for crystal deposition. Tissue specimen of the femoral head or synovial fluid was obtained by resection of the necrotic parts, or by bone - biopsy drilling procedure or by arthrocentesis of the hip. The examination furtheron was done histological and by polarized light. On 10 patients typical results caused by monosodium urate crystals were found. This was demonstrated on several cases. This results may lead to postulate that hyperuricaemia may have played a causative role and has to be kept in mind by treating uric acid disorders. Whatever the relationship, there is nothing specific about the radiographic finding which would allow one to suspect the presence of gout or hyperuricaemia.

Zusammenfassung

38 Patienten mit einer Osteonekrose der Hüfte wurden untersucht. Das gewonnene Material (Knochen/Synovialflüssigkeit) wurde histologisch und polarisationsoptisch auf Uratkristallablagerungen hin untersucht. Bei 10 Patienten konnte ein typischer Befund erhoben werden und wurde auch an Hand einiger Fallbeispiele demonstriert.