Seven epileptic patients with permanent ataxic dysfunction following DPH treatment
are described. The ataxia correlates with cerebellar atrophy, though the extents of
clinical and structural lesions are not necessarily proportional. Cerebellar atrophy
is demonstrated by CT scans, the vermal region seems to be predominantly affected.
- The tentatively increased susceptibility of female patients and of patients with
pre-existing brain lesions, as well as the possible consequences pertaining to the
course of the epilepsy are discussed.
Epilepsy - Diphenylhydantoin - Cerebellar atrophy - Computerized tomography
