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Neuropediatrics 1985; 16(3): 115-120
DOI: 10.1055/s-2008-1052554
ORIGINAL ARTICLES

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Cerebrospinal Fluid Dynamics and Cerebrospinal Fluid Infusion in Children - Part I: A Revised Method and a Review

R. H. Gooskens1 , J.  Willemse1 , C.  Gielen2
  • 1Department of Child Neurology, University Hospital Utrecht, Catharijnesingel 101, 3500 CG Utrecht, The Netherlands
  • 2Department of Medical Physics, University of Utrecht, Princetonplein 5, 3485 CC Utrecht, The Netherlands
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Publication History

Publication Date:
16 May 2008 (online)

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Cerebrospinal Fluid Dynamics and Cerebrospinal Fluid Infusion in Children - Part II: Clinical Application of Lumbar Cerebrospinal Fluid Infusion in Children with Macrocephaly and Normal Growth Rate of the Head CircumferenceNeuropediatrics 1985; 16(03): 121-125
DOI: 10.1055/s-2008-1052555

Abstract

In the study of cerebrospinal fluid dynamics in children with macrocephaly, the lumbar CSF infusion technique has always been used. Previous studies showed, that the regulation of cerebrospinal fluid dynamics are mainly determined by Pressure-Volume Index (PVI) and outflow resistance (Ro). Recent studies have shown, that the relationship between pressure and volume is mono exponential with a constant. This result suggests a third parameter c. PVI, Ro and c were determined with a combination of bolusmethod and a constant flow infusion.

Key words

Cerebrospinal fluid dynamics - Cerebrospinal fluid infusion