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Aktuelle Urol 1996; 27: 25-26
DOI: 10.1055/s-2008-1055642
© Georg Thieme Verlag, Stuttgart · New York

Effect and Safety of Tamsulosin, the Prostate Specific α1-Blocker, in the Treatment of BPH (Benign Prostatic Hyperplasia)

K. Kawabe
  • Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
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Publication History

Publication Date:
19 March 2008 (online)

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Summary:

Clinical trials of tamsulosin demonstrate that it is an effective treatment modality for the symptoms associated with BPH, and it has practically no effect on blood pressure at a dose of 0.2 mg. This is probably due to its selective affinity for the prostate, which may be due to the strong affinity of tamsulosin for the α1a-receptor subtype.

Key words:

BPH, α-blocker, - α1a-receptor-subtype - Tamsulosin