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Semin intervent Radiol 1998; 15(4): 365-371
DOI: 10.1055/s-2008-1057029
Copyright © 1998 by Thieme Medical Publishers, Inc.

Regional Therapy of High Grade Astrocytomas

James V. Manzione, Stefan Madajewicz, Clemente Roque, Patricia Roche, Arafat Tfayli, Maisie L. Shindo
  • Department of Radiology, Department of Medicine, and Department of Surgery, State University of New York at Stony Brook, Stony Brook, New York
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Publication Date:
21 May 2008 (online)

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Abstract

High grade astrocytomas are difficult to treat surgically due to the diffuse nature of these lesions. Systemic chemotherapy has poor results due to limited penetration into the tumor and systemic toxicity. Regional therapy of high grade astrocytomas represents a promising new approach to these lesions. This article reviews recent experience with intraarterial chemotherapy in the treatment of these lesions.

Keywords:

Astrocytomas - chemotherapy - regional therapy