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Synthesis 2008(12): 1938-1942
DOI: 10.1055/s-2008-1067089
DOI: 10.1055/s-2008-1067089
PAPER
© Georg Thieme Verlag Stuttgart · New York
A Concise Stereoselective Total Synthesis of Herbarumin III
Further Information
Received
27 February 2008
Publication Date:
16 May 2008 (online)
Publication History
Publication Date:
16 May 2008 (online)
Abstract
A stereoselective total synthesis of the phytotoxic compound herbarumin III has been achieved by utilizing Crimmins’s aldol approach, 1,3-syn asymmetric reduction, and an olefin metathesis reaction as the key steps.
Key words
macrolide - phytotoxic - Crimmins aldol reaction - syn reduction - olefin metathesis
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