Synthesis 2008(19): 3108-3120  
DOI: 10.1055/s-2008-1067266
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Carbohydrate-Based Spiro-1,3-oxazolidine-2-thiones: Stereoselective Approaches Using Aziridines and Epoxides

Sébastien Tardya, Joana Lobo Vicentea, Arnaud Tatibouët*a, Gilles Dujardinb, Patrick Rollina
a ICOA UMR 6005 CNRS, Université d’Orléans, 45067 Orléans, France
e-Mail: arnaud.tatibouet@univ-orleans.fr;
b UCO2M UMR 6011 CNRS, Université du Maine, 72085 Le Mans, France
Further Information

Publication History

Received 30 April 2008
Publication Date:
05 September 2008 (online)

Abstract

d-glucose and d-fructose have been used as starting materials to prepare spiro-1,3-oxazolidine-2-thiones anchored on the third position of both carbohydrates. Following different ap­proaches and depending on the carbohydrate template explored, stereoselective reactions have been developed via the formation of epoxides or aziridines.