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Neuropediatrics 1992; 23(5): 235-240
DOI: 10.1055/s-2008-1071349
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Cerebro-Spinal Fluid Eosinophilia in Shunt Infections

M.  Vinchon1 , L.  Vallee2 , L.  Prin3 , P.  Desreumaux3 , P.  Dhellemmes1
  • 1Service de Neurochirurgie Pédiatrique, Hôpital B, CHRU, Lille, Cedex, France
  • 2Service des Maladies Infectieuses et de Neurologie Infantiles. Hôpital B. CHRU, Lille, Cedex, France
  • 3Laboratoire d'Immunologie et de Parasitologie, Institut Pasteur, Lille, Cedex, France
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

Hypereosinophilia has been detected in the CSF of 22 patients in a series of 81 cases of shunt infection. It was related with the evolution of the sepsis. Its persistence at the end of treatment appeared to predict later complications, septic or obstructive, and it could be the sign of latent infection. HE might be the result of a specific reaction directed against the infected material, but a non-specific process cannot be eliminated.

Key words

Hydrocephalus - CSF shunt infection - CSF eosinophilia - Eosinophil granulocyte - Silicone rubber