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Neuropediatrics 1991; 22(3): 166-167
DOI: 10.1055/s-2008-1071436
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Therapeutic Effect of Sodium Dichloroacetate on Visual and Auditory Hallucinations in a Patient with MELAS

T.  Saijo , E.  Naito , M.  Ito , E.  Takeda , T.  Hashimoto , Y.  Kuroda
  • Department of Pediatrics, School of Medicine, University of Tokushima, Kuramoto 3, Tokushima 770, Japan
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

We report a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes who experienced visual and auditory hallucinations. His blood and cerebrospinal fluid lactate levels were remarkably elevated. Sodium dichloroacetate was administered orally at doses of 12.5 to 100 mg/kg/day. On normalization of the lactate levels, the hallucinations disappeared.

Key words

Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes - Sodium dichloroacetate - Lactate - Hallucination