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Neuropediatrics 1991; 22(4): 216-219
DOI: 10.1055/s-2008-1071444
Original article

© Georg Thieme Verlag KG Stuttgart · New York

EEG Findings in Hypomelanosis of Ito

E. E. Esquivel , M. C. Pitt , S. G. Boyd
  • Department of Clinical Neurophysiology, The Hospital for Sick Children, Great Ormond Street, London WC1N 3JH, U.K.
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

The EEG findings in 15 children with Hypomelanosis of Ito have been reviewed and related to the clinical and CT scan data. Although no consistent electroclinical associations were found in the group as a whole, there was some association between the presence of abnormal rhythmic EEG activity and the radiological appearances of neuronal migration defects. In addition, the possibility is raised that there may be a distinctive sub-group of children with Ito's syndrome who present with an early onset of intractable seizures and who have a neuronal migration defect.

Key words

Hypomelanosis of Ito - Neuronal migration defect - EEG