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Neuropediatrics 1990; 21(4): 193-198
DOI: 10.1055/s-2008-1071494
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Cranial MR Imaging in Patients with von Recklinghausen's Disease (Neurofibromatosis Type I)

T.  Hashimoto1 , M.  Tayama1 , M.  Miyazaki1 , Y.  Kuroda1 , K.  Hiura2 , K.  Hujino3 , K.  Yamashita4
  • 1Department of Pediatrics, Tokushima University School of Medicine, Kuramoto-cho 3, Tokushima 770, Japan
  • 2Department of Pediatrics, Anan Kyohei Hospital, Nakasho Hanoura-cho, Naka country, Tokushima 779-11, Japan
  • 3Department of Pediatrics, Komatsushima Red Cross Hospital, 28-1 Shingai Chuden-cho, Komatsushima City, Tokushima 773, Japan
  • 4Department of Pediatrics, Tokushima Municipal Hospital, 2-34 Kita Jyosanjima-cho, Tokushima 770, Japan
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

MR imaging was performed for 24 patients with von Recklinghausen's disease. Twenty of the 24 patients showed abnormal findings in MR imaging. In many cases, the lesions were multifocal. In 14 patients small focal areas of increased signal on T2-weighted images were thought to represent heterotopias or hamartomas. Eight patients had optic tract gliomas. Three patients had parenchymal gliomas. In one patient, white matter showed high intensity on T2-weighted images representing delayed myelination.

The rate of abnormal findings was higher for MR imaging than CT. MR imaging was found to be an excellent imaging method for known diseases and for detecting lesions in asymptomatic patients.

Key words

Neurofibromatosis - Von Recklinghausen's disease - MR imaging - CT