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Neuropediatrics 1993; 24(1): 47-50
DOI: 10.1055/s-2008-1071512
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Regional Cerebral Blood-Flow Measured by HMPAO and SPECT in a 5-Year-Old Boy with Landau-Kleffner Syndrome

S. E. Mouridsen1 , Charlotte  Videbœk2 , Hanne  Søgaard3 , A. R. Andersen
  • 1Department of Child Psychiatry, Rigshospitalet, Copenhagen, Denmark
  • 2Department of Neurology, Rigshospitalet, Copenhagen, Denmark
  • 3Department of Child Psychiatry, Rigshospitalet, Copenhagen, Denmark
  • 4Department of Neurology, Rigshospitalet, Copenhagen, Denmark
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Publikationsdatum:
19. März 2008 (online)

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Abstract

We present a 5-year-old boy with Landau-Kleffner syndrome, whose clinical manifestations were very similar to cases previously reported in the literature. CT and MRI scan failed to document any morphological abnormalities of his brain. However, high resolution rCBF imaging by HMPAO and SPECT demonstrated relatively low-flow areas in the left middle frontal gyrus and the right mesiotemporal/hippocampal region corresponding to the localization of EEG changes.

Key words

Landau-Kleffner syndrome - Acquired aphasia of childhood - SPECT - HMPAO - Regional cerebral blood flow