Constituents from Hoya parasitica and their Cell Growth Inhibitory Activity

Abstract

An androstanoid, hoyasterone (1), a sesquiterpene, 15-bulnesolic acid (2), and a phenolic compound, 1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropan-2-ol (3), together with a known triterpene, dihydrocanaric acid, were isolated from Hoya parasitica. Structures were elucidated by 1 D and 2 D NMR and mass spectroscopic analysis. Among the isolated compounds, only dihydrocanaric acid exhibited growth inhibitory activity against both HeLa and SW480 cells.

Key words

Hoya parasitica - Asclepiadaceae - hoyasterone - 15-bulnesolic acid - 1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropan-2-ol - cell growth inhibitory activity

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