Planta Med 2008; 74(8): 873-879
DOI: 10.1055/s-2008-1074562
Analytical Studies
Original Paper
© Georg Thieme Verlag KG Stuttgart · New York

Comparison of Phenolic Compounds of Rhubarbs in the Section Deserticola with Rheum palmatum by HPLC-DAD-ESI-MSn

Jian Han1 , Min Ye1 , Man Xu1 , Xue Qiao1 , Hubiao Chen2 , Baorong Wang1 , Junhua Zheng1 , De-an Guo1
  • 1School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, P. R. China
  • 2School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, P. R. China
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Publikationsverlauf

Received: February 3, 2008 Revised: May 3, 2008

Accepted: May 5, 2008

Publikationsdatum:
18. Juni 2008 (online)

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Abstract

A sophisticated LC-ESI-MSn method was utilized for the analysis of the phenolic compounds in five unofficial Rheum species for the first time. These species belong to the section deserticola Maxim. of the Polygonaceae family, including Rheum racemiferum Maxim., R. nanum Siev. ex Pall., R. delavayi Franch., R. sublanceolatum C. Y. Cheng et T. C. Kao and R. pumilum Maxim. A total of 101 phenolic compounds, including sennosides, anthraquinones, stilbenes, glucose gallates, naphthalenes, procyanidins and chromones were identified or tentatively characterized based on their UV and mass spectral data from the methanol extracts. These chemical constituents were compared with those of an official species (R. palmatum L.). The results showed that most sennosides and procyanidin derivatives were only present in R. palmatum rather than in the unofficial species; stilbenes and chromones were only found in the sect. deserticola species; while anthraquinones, glucose gallates and naphthalenes could be detected in all studied species. For anthraquinone glycosides, only emodin O-glucosides were detected in the sect. deserticola species. Moreover, remarkable difference was observed among unofficial species. These results may be useful for the quality control of rhubarb in order to guarantee its clinical effects, and may also be helpful for the further clarification of the taxonomic relationship of the plants in the sect. deserticola.

References

Prof. Dr. De-an Guo

School of Pharmaceutical Sciences

Peking University Health Science Center

Beijing 100083

People’s Republic of China

Telefon: +86/10/8280/1516

Fax: +86/10/8280/2700

eMail: gda@bjmu.edu.cn