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Planta Med 1980; 38(2): 151-154
DOI: 10.1055/s-2008-1074852
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Screening of Euphorbia from Azarbaijan for Skin Irritant Activity and for Diterpenes

R. R. Upadhyay, F. Bakhtavar, H. Mohseni, A. M. Sater, N. Saleh, A. Tafazuli, F. N. Dizaji, G. Mohaddes
  • Department of Pharmacognosy, Faculty of Pharmacy, Azarabadegan University Tabriz, Iran.
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Publication History

Publication Date:
29 April 2008 (online)

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Abstract

Fifteen of nineteen Euphorbia species growing in the Azarbaijan province of Iran were screened for their skin irritant properties. All except E. herbecarpa Boiss, E. orientalis L. and E. peploid Gouan, were found to possess the diterpene ingenol, the fatty acid esters of which are known to be skin irritants. No phorbol esters or other irritants could be detected.

Key Word

Index: Euphorbiaceae - Ingenol 3,5,20-triacetate - Skin irritants.