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DOI: 10.1055/s-2008-1078414
Mechanistic Studies on the Roles of Cosolvents and Additives in Samarium(II)-Based Reductions
Publication History
Publication Date:
16 May 2008 (online)
![](https://www.thieme-connect.de/media/synlett/200810/lookinside/thumbnails/10.1055-s-2008-1078414-1.jpg)
Abstract
This account describes work, performed by my research group during the past decade, designed to understand the mechanistic roles of cosolvents and additives in reductions involving samarium(II) iodide (SmI2). Emphasis is placed on studies designed to elucidate the roles of the cosolvent hexamethylphosphoramide (HMPA) and proton donors (water, alcohols, and glycols) in the mechanisms of important bond-forming reactions and reductions initiated by SmI2.
1 Background and Introduction
1.1 Project Inception
2 Mechanistic Studies on the Role of Hexamethylphosphoramide in the Reactions of Samarium(II) Iodide
3 Impact of Proton Donors on the Mechanism of Substrate Reduction
4 Conclusions and Future Work
Key words
samarium(II) iodide - electron transfer - hexamethylphosphoramide - proton donors - reductions
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