Ossified Frontosphenoorbital Meningioma en plaque, Mimicking Extensive Hyperostosis

Abstract

Small intratumoral calcifications are often seen within meningioma, but ossification of the whole neoplasm is very rare. The case of an ossified frontosphenoorbital meningioma en plaque is presented. The radiological appearance resembled extensive hyperostosis extending from the anterior clinoid process to the cerebral convexity and falx cerebri. It is possible that, in some cases of meningioma, the identified “hyperostosis” represents partial ossification of the tumor itself.

Key words

meningioma en plaque - ossified meningioma - hyperostosis - metaplasia

References

• 1 Louis DN, Scheithauer BW, Budka H, von Deimling A, Kepes JJ. Meningiomas. In: Kleihues P, Cavenee WK, eds. Pathology and genetics of tumours of the nervous system. Lyon: IARC Press 2000: 176-184
• 2 Kitagawa M, Nakamura T, Aida T, Iwasaki Y, Abe H, Nagashima K. Clinicopathologic analysis of ossification in spinal meningioma.  Noshuyo Byori. 1994;  11 115-119 , (in Japanese)
• 3 Naderi S, Yilmaz M, Canda T, Acar U. Ossified thoracic spinal meningioma in childhood: a case report and review of the literature.  Clin Neurol Neurosurg. 2001;  103 247-249
• 4 Liu CL, Lai PL, Jung SM, Liao CC. Thoracic ossified meningioma and osteoporotic burst fracture: treatment with combined vertebroplasty and laminectomy without instrumentation: case report.  J Neurosurg Spine. 2006;  4 256-259
• 5 Cushing H, Eisenhardt L. Meningiomas: their classification, regional behavior, life history and surgical end results. Springfield: Charles C. Thomas 1938
• 6 Pieper DR, AL-Mefty O, Hanada Y, Buechner D. Hyperostosis associated with meningioma of the cranial base: secondary changes or tumor invasion.  Neurosurgery. 1999;  44 742-747
• 7 Jesus O De, Toledo MM. Surgical management of meningioma en plaque of the sphenoid ridge.  Surg Neurol. 2001;  55 265-269
• 8 Honeybul S, Neil-Dwyer G, Lang DA, Evans BT, Ellison DW. Sphenoid wing meningioma en plaque: a clinical review.  Acta Neurochir (Wien). 2001;  143 749-758
• 9 Shrivastava RK, Sen C, Costantino PD, Della Rocca R. Sphenoorbital meningiomas: surgical limitations and lessons learned in their long-term management.  J Neurosurg. 2005;  103 491-497
• 10 Bikmaz K, Mrak R, Al-Mefty O. Management of bone-invasive, hyperostotic sphenoid wing meningiomas.  J Neurosurg. 2007;  107 905-912
• 11 Min JH, Kang SH, Lee JB, Chung YG, Lee HK. Hyperostotic meningioma with minimal tumor invasion into the skull.  Neurol Med Chir (Tokyo). 2005;  45 480-483
• 12 Kim KS, Rogers LF, Goldblatt D. CT features of hyperostosing meningioma en plaque.  AJR Am J Roentgenol. 1987;  149 1017-1023
• 13 Daffner RH, Yakulis R, Maroon JC. Intraosseous meningioma.  Skeletal Radiol. 1998;  27 108-111

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